Biological Sensors
BEADS Automated Immunoassays (259)
Problem: Need immunoassays for detection of analytes that are optimized for dilute solutions
Project Activity Scope (from Technical Overview Chart): Sensors and Devices through Instruments
PNNL Solution:
- Renewable Bead-based immunoassay column more efficient than existing manual methods
- Improvement in analysis time
- Optional recirculation of sample to enhance analyte capture
- Successfully demonstrated for TNT, pesticide/herbicide detection and Botulinum toxin detection in water
Capabilities Employed to Meet Client Needs: System architecture; mesofluidics; renewable column technology; sample cell with magnetic column or rotating rod column for reliable sample exchange.
Selected Links to Related Information:
- Related Examples (Same Project)
- BEADS for Selective Analyte Capture (407)
- Automated BEAD Suspension Arrays (254)
- Automated Fluidics for BEADS Sensors (411)
- Automated Toxin Detection System (412)
- BEADS: A Basic Tool for Bio-Detection (255)
- BEADS: Automated Sample Processing System for Biodetection (260)
- Beads for Separations, Processing, Sensing (261)
- Nucleic Acid Extraction and Purification (408)
- Renewable Chem-Bio Sensor System (409)
- "Reporters" Indicate Target Analyte Capture (410)
- Similar Technology Examples (Same or Different Application)
- Related Websites
- Breakthroughs, Winter/Spring 2002 (.pdf 7.3MB - see second item)
- BEADS (Biodetection Enabling Analyte Delivery System) Sample Preparation Technology
Contact: Cindy Bruckner-Lea
