Biological Sensors
BEADS: Automated Sample Processing System for Biodetection (260)
Problem: Need field deployable sample processing system for environmental and clinical samples prior to biodetection
Project Activity Scope (from TechnicalOverview Chart): Sensors and Devices through Integrated Systems
PNNL Solution:
- Automated "BEADS" technology for efficient analyte extraction from complex samples
- Analyte is concentrated and purified
- Field portable, self-contained unit
- Optional cell lysis, DNA amplification, and optical detection integrated into unit
Capabilities Employed to Meet Client Needs: Bead attachment chemistry; antibody development; renewal filter system development; bead handling methodologies; sample cell design for reliable bead exchange (rotating rod concept); fluidic systems; interface requirements to multiple sensor/detection technologies, anti-body development.
Selected Links to Related Information:
- Related Examples (Same Project)
- BEADS: A Basic Tool for Bio-Detection (255)
- Renewable Chem-Bio Sensor System (409)
- Automated BEAD Suspension Arrays (254)
- Automated Fluidics for BEADS Sensors (411)
- Automated Toxin Detection System (412)
- BEADS Automated Immunoassays (259)
- Beads for Separations, Processing, Sensing (261)
- Ultrasonic Biological Cell Disruption (258)
- "Reporters" Indicate Target Analyte Capture (410)
- Similar Technology Examples (Same or Different Application)
- Related Websites
- Breakthroughs, Winter/Spring 2002 (.pdf 7.3MB - see second item)
- BEADS (Biodetection Enabling Analyte Delivery System) Sample Preparation Technology
Contact: Cindy Bruckner-Lea
