Sensors & Electronics
Biological Sensors
Alternate Methods to Monitor Stress Effects (446)
Problem: Determine preferred mRNA measurement method for evaluating environmental exposure effects.
Project Activity Scope (from Technical Overview Chart): Mechanisms through Sensors and Devices.
PNNL Solution:
- Two technical approaches were used to monitor mRNA stress response
- Dual array method required less sample preparation but used two arrays
- Two-color array required extra sample processing step but only used one array
- Comparative tests under way to determine most effective approach
Capabilities Employed to Meet Client Needs: Array preparation, hybridization, and data analysis.
Selected Links to Related Information:
- Related Examples (Same Project)
- Similar Application Examples (Same or Different Technology)
- Related Websites
- Microarrays: Chipping Away at the Mysteries of Science and Medicine — A Science Primer, National Center for Biotechnology Information, US National Institutes of Health, July 2007
Contact: Tim Straub
