Sensors & Electronics
Biological Sensors
Tailored DNA Detector Array Preparation (457)
Problem: Need to prepare arrays that are tailored to detect specific organisms and DNA/mRNA fragments.
Project Activity Scope (from Technical Overview Chart): Mechanisms through Sensors and Devices.
PNNL Solution:
- Determined key DNA fragments for target microorganism(s) using complementary analysis tools
- Selected and procured DNA fragments for effective capture of key micro-organism fragments
- Prepared test arrays by attaching "tether" DNA fragments to substrate using pattern printer
Capabilities Employed to Meet Client Needs: Oligonucleotide selection, array printing, experimental design.
Selected Links to Related Information:
- Related Examples (Same Project)
- Alternate Methods for Organism Detection (455)
- Broad Response DNA Detector Arrays (458)
- Concentrate Microorganisms for Analysis (453)
- Conceptual Introduction to DNA Basics (450)
- DNA Array Basics (451)
- Organism Identification from Array Response (459)
- Organism Specific DNA Detector Arrays (456)
- Very Selective Detection with DNA Arrays (454)
- Water Screening for Microorganism Hazards (452)
- Similar Technology Examples (Same or Different Application)
Contact: Tim Straub
