Sensors & Electronics
Biological Sensors
Organism Identification from Array Response (459)
Problem: Read sensor arrays to obtain quantitative data and analyze data to determine microorganism identification.
Project Activity Scope (from Technical Overview Chart): Sensors and Devices through Instruments.
PNNL Solution:
- "Read" exposed arrays to find pixels with bound DNA fragments
- If there were active pixels, then there were microorganisms in water
- Compared array to patterns for target and known microorganisms
- If the pattern matched the target organism (or a known organism), reported the organism identification
- If not, unknown organism present
Capabilities Employed to Meet Client Needs: Array detection and analysis, data interpretation, quality control.
Selected Links to Related Information:
- Related Examples (Same Project)
- Alternate Methods for Organism Detection (455)
- Broad Response DNA Detector Arrays (458)
- Concentrate Microorganisms for Analysis (453)
- Conceptual Introduction to DNA Basics (450)
- DNA Array Basics (451)
- Organism Specific DNA Detector Arrays (456)
- Tailored DNA Detector Array Preparation (457)
- Very Selective Detection with DNA Arrays (454)
- Water Screening for Microorganism Hazards (452)
- Similar Application Examples (Same or Different Technology)
- Related Websites
- Microarrays: Chipping Away at the Mysteries of Science and Medicine — A Science Primer, National Center for Biotechnology Information, US National Institutes of Health, July 2007
Contact: Tim Straub
