Biolgical Sensors
Enzyme Immobilization for Chem-Bio Sensors (288)
Problem: Need to immobilize and increase effective lifetime of enzymes to improve the efficacy of enzyme-based sensors
Project Activity Scope (from Technical Overview Chart): Mechanisms through Sensors and Devices
PNNL Solution:
- Enzymes stabilized in surface activated mesoporous silica structure exhibit activity increased from hours to over 6 months
- Successfully demonstrated with multiple enzymes to increase activity significantly
- Target applications are small, robust, sensitive detectors and reactors
Capabilities Employed to Meet Client Needs: Mesoporous surfaces, surface functionalization chemistry, enzyme modification, bio-structural modeling, fluorescence chemistry, electro-chemistry.
Selected Links to Related Information:
- Related Examples (Same Project)
- Related Websites
- See information in PNNL News article "Enzyme discovery to benefit homeland security, industry"
- See information at Self-Assembled Monolayers on Mesoporous Supports (SAMMS) website
Contact: Eric Ackerman
