Sensors & Electronics
Biological Sensors
Water Screening for Microorganism Hazards (452)
Problem: Ensure drinking water safety by timely detection of any hazardous microorganisms (natural or man-introduced).
Project Activity Scope (from Technical Overview Chart): Mechanisms through Instruments.
PNNL Solution:
- Pre-concentrate microorganisms from large volume water sample
- Exploit DNA binding for selective organism capture
- Specific analysis for microorganisms
- Broad response to test for range of microorganisms
- Analyze data and approve or reject water for safe consumption
- Water screening capability for hazardous microorganisms
Capabilities Employed to Meet Client Needs: Bead attachment chemistry, antibody development, renewal filter system development, bead handling methodologies, sample cell design for reliable bead exchange (rotating rod concept), fluidic systems, interface requirements to multiple sensor/detection technologies.
Selected Links to Related Information:
- Related Examples (Same Project)
- Alternate Methods for Organism Detection (455)
- Broad Response DNA Detector Arrays (458)
- Concentrate Microorganisms for Analysis (453)
- Conceptual Introduction to DNA Basics (450)
- DNA Array Basics (451)
- Organism Specific DNA Detector Arrays (456)
- Organism Identification from Array Response (459)
- Tailored DNA Detector Array Preparation (457)
- Very Selective Detection with DNA Arrays (454)
- Similar Technology Examples (Same or Different Technology)
Contact: Richard Ozanich
