Biological Sensors
Optical Signatures of Bacteria (330)
Problem: Need method to rapidly detect and identify bacteria
Project Activity Scope (from Technical Overview Chart): Mechanisms through Sensors and Devices
PNNL Solution:
- Infrared spectra measured for various bacteria (in dry form) exhibit exploitable signatures
- Evaluate spectra for a number of organisms to: a) determine key signatures, b) evaluate potential importance of interferences, and c) expand to mixtures
- Expand signature library
- Published findings
Capabilities Employed to Meet Client Needs: Spectroscopic understanding of molecules and bacteria; use of electronics to collect data; data processing and analysis; understanding and operation of FT-infrared spectrometers for spectra characterization; microbiological techniques in cell culturing; statistical analysis of large, complex data sets, data analysis to obtain key chemical and biological information; reporting of findings (including numerous open literature publications).
Selected Links to Related Information:
- Similar Application Examples (Same or Different Technology)
- Similar Technology Examples (Same or Different Application)
Contact: Nancy Foster-Mills
