Biological Sensors
Non-Invasive Biomonitoring (257)
Problem: Need non-invasive approaches for monitoring chemical exposure of personnel and animals
Project Activity Scope (from Technical Overview Chart): Mechanisms through Integrated Systems
PNNL Solution:
- Use of saliva, urine and breath to replace blood in monitoring chemical exposure
- Integrated microfluidic/ electro-chemical sensor platform increases sample throughput, reduces analysis time, sample quantity, cost
- Demonstrated lead detection in saliva
- Applicable to mixtures of heavy metals and many organic compounds including organophosphates (pesticides, chemical warfare agents)
Capabilities Employed to Meet Client Needs: Animal modeling; toxicology, electrochemical sensors; micro-fluidics; statistical data analysis, physiologically based pharmacokinetic (PBPK) modeling; GC-MS.
Selected Links to Related Information:
- Similar Application Examples (Same or Different Technology)
- Similar Technology Examples (Same or Different Application)
- Compact Electrochemical Sensor Cells (280)
- High-Performance Preconcentrator Materials (277)
- Integrated Microfluidics for Sensors (279)
- Ion-Specific Sensors for Metals in Solutions (275)
- Measurement of Metal Ions in Solution (282)
- Portable Electrochemical Sensor System (281)
- Preconcentration for Improved Detection (276)
- Preconcentration Material for Heavy Metals (278)
- Related Websites
Contact: Charles Timchalk
