Sensors & Electronics
Biological Sensors
Concentrate Microorganisms for Analysis (453)
Problem: Pre-concentrate very dilute microorganisms from large volumes of water to ensure reliable organism detection.
Project Activity Scope (from Technical Overview Chart): Mechanisms through Sensors and Devices.
PNNL Solution:
- Health effects occur at very low microorganism concentrations
- Selective pre-concentration increases target organism levels without increasing background
- PNNL Biodetection Enabling Analyte Delivery System (BEADS) enables concentration and purification of microorganisms
Capabilities Employed to Meet Client Needs: Bead attachment chemistry, antibody development, renewal filter system development, bead handling methodologies, sample cell design for reliable magnetic and non-magnetic bead exchange (rotating rod and electromagnetic trap/flow-cell concept), fluidic systems, interface requirements to multiple sensor/detection technologies.
Selected Links to Related Information:
- Related Examples (Same Project)
- Alternate Methods for Organism Detection (455)
- Broad Response DNA Detector Arrays (458)
- Conceptual Introduction to DNA Basics (450)
- DNA Array Basics (451)
- Organism Identification from Array Response (459)
- Organism Specific DNA Detector Arrays (456)
- Tailored DNA Detector Array Preparation (457)
- Very Selective Detection with DNA Arrays (454)
- Water Screening for Microorganism Hazards (452)
- Similar Technology Examples (Same or Different Application)
- Automated Fluidics for BEADS Sensors (411)
- BEADS: A Basic Tool for Bio-Detection (255)
- BEADS Automated Immunoassays (259)
- BEADS: Automated Sample Processing System for Biodetection (260)
- BEADS for Selective Analyte Capture (407)
- BEADS for Separations, Processing, Sensing (261)
- Integrated Microbial Forensics (423)
- Integrated Microfluidics for Sensors (279)
- Nucleic Acid Extraction and Purification (408)
- Rapid Antibody Production Using Yeast (231)
- Related Websites
Contact: Richard Ozanich
