Sensors & Electronics
Electronics & Systems
Hand Held Biological Threat Detector (418)
Problem: Need rapid, easy to use, handheld portable sensor to provide sensitive, selective detection of target bio-threats.
Project Activity Scope (from Technical Overview Chart): Sensors and Devices through Instruments.
PNNL Solution:
- Leverage fluorescence based threat bio-threat detection mechanisms
- Develop sealed cassettes for simple sample handing and sample archiving
- Develop compact instrument design including sample cassette, optical detection, electronics, mechanical housing, software, and user interface subsystems
- Can use aptamer or antibody assays
- Unit sealed for easy decontamination
Capabilities Employed to Meet Client Needs: Development of selective coatings for target analytes; surface functionalization; nano-beads and micro-beads used with renewable magnetic and non-magnetic bead-trapping flow cells for sensing applications; application of coatings to micro-beads for practical usage including utilization of reporter technologies to enable detection (fluorophores, quenchers); development of automated fluidic systems for micro-bead and test solution manipulation; development of electronic and package components for prototype system; software development for instrument control and data processing; fabrication, and evaluation; laboratory testing and validation with real-world complex samples; establish intellectual property position; publication of key results.
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Contact: Mike Lind
